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Invitrogen™ ITGA3 Polyclonal Antibody
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Catalog No. PIPA599407
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100 μL
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PIPA599407 100 μL
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Catalog No. PIPA599407 Supplier Invitrogen™ Supplier No. PA599407
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total Integrin alpha 3.

ITGA3 (INTEGRIN, ALPHA-3), also called CD49C, VLA3 or GAPB3, is a protein that in humans is encoded by the ITGA3 gene. ITGA3 is an integrin alpha subunit which is also a member of the family of cell surface adhesion molecules. ITGA3 is mapped to chromosome 17 and its exact cytogenetic location is 17q21.33. ITGA3 makes up half of the alpha3beta1 integrin duplex that plays a role in neural migration and corticogenesis together with beta-1 subunit. A functional link between DAB1 phosphorylation and ITGA3 signaling drives the timely detachment of migrating neurons from radial glial fibers. Expression of human ITGA3 increased the infectivity of virus for Chinese hamster ovary cells. ITGA3 also contains 13 potential N-glycosylation sites, 2 potential cleavage sites, and the 7 N-terminal repeating units characteristic of ITGAs. Recombinant ITGA3 is expressed as a 150-kD protein as the same size as the native protein by the western blot analysis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ITGA3
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene ITGA3
Gene Accession No. P26006, Q62470
Gene Alias AA407068; alpha 3 subunit of VLA-3 receptor; Alpha3 integrin; antigen CD49C; antigen identified by monoclonal antibody J143; CD49 antigen-like family member C; CD49c; CD49c antigen; FLJ34631; FLJ34704; FRP-2; Galactoprotein B3; GAPB3; GAP-B3; ILNEB; integrin alpha 3; Integrin alpha3; Integrin alpha-3; Integrin alpha-3 heavy chain; Integrin alpha-3 light chain; integrin subunit alpha 3; integrin, alpha 3; integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor); ITGA3; MSK18; testicular tissue protein Li 96; testicular tissue protein Li 98; VCA-2; very late activation protein 3 receptor, alpha-3 subunit; VL3A; VLA-3 subunit alpha; VLA3a
Gene Symbols ITGA3
Host Species Rabbit
Immunogen A synthesized peptide derived from human ITGA3(Accession P26006), corresponding to amino acid residues C496-P546.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 16400, 360606, 3675
Target Species Human, Mouse, Rat, Monkey
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

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