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Tocris Bioscience™ Itraconazole

SMO antagonist; acts at different binding site to cyclopamine (Cat No. 1623)

Supplier:  Tocris Bioscience™ 5981/50

Catalog No. 59-815-0


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Description

Description

Itraconazole is a SMO antagonist (IC50 = 690 nM); acts at different binding site to cyclopamine (Cat. No. 1623). Also cytochrome p450 inhibitor (IC50 = 16-26 nM). Inhibits cell cycle at G1 phase in vitro and blocks angiogenesis in vivo (IC50 = 160 nM). Antifungal.
Specifications

Specifications

4-[4-[4-[4-[[2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-2,4-dihydro-2-(1-methylpropyl)-3H-1,2,4-triazol-3-one
50 mg
C35H38Cl2N8O4
>99%
84625-61-6
Smoothened Receptor Antagonists
705.63
Safety and Handling

Safety and Handling

Recommended Storage : Store at -20°C

SDS
Documents

Documents

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