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Tocris Bioscience™ Itraconazole



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Quantity:
50 mg
Description
Itraconazole is a SMO antagonist (IC50 = 690 nM); acts at different binding site to cyclopamine (Cat. No. 1623). Also cytochrome p450 inhibitor (IC50 = 16-26 nM). Inhibits cell cycle at G1 phase in vitro and blocks angiogenesis in vivo (IC50 = 160 nM). Antifungal.
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Specifications
Specifications
Chemical Name or Material | 4-[4-[4-[4-[[2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-2,4-dihydro-2-(1-methylpropyl)-3H-1,2,4-triazol-3-one |
CAS | 84625-61-6 |
Quantity | 50 mg |
Target | Smoothened Receptor Antagonists |
Molecular Formula | C35H38Cl2N8O4 |
Formula Weight | 705.63 |
Purity | >99% |
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