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  5. Tocris Bioscience™ IWP 12

Tocris Bioscience™ IWP 12

Catalog No. 527950
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Potent PORCN inhibitor; active in vivo

IWP 12 is a potent inhibitor of Porcupine (PORCN), a membrane-bound O-acyltransferase (MBOAT) (IC50 = 15 nM). Inhibits Wnt/β-catenin and Wnt/planar cell polarity (PCP) signaling pathways. Blocks zebrafish tailfin regeneration in vivo.

Specifications

Purity >98%
Quantity 50 mg
Product Type IWP 12
Molecular Weight (g/mol) 418.56
Inhibitors IWP 12

For Research Use Only

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