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Invitrogen™ JAB1 Monoclonal Antibody (8H8.5)
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Catalog No. PIMA123248
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100 μL
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Catalog No. Quantity
PIMA123248 100 μL
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Catalog No. PIMA123248 Supplier Invitrogen™ Supplier No. MA123248
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Description

Mouse Monoclonal Antibody

Recommended positive controls: 293 cell lysate.

JAB-1 is a 38 kDa protein which was originally described as a coactivator for cJUN. It is present in a large protein complex called the 'Signalosome', which has been proposed to play a signaling role in mammalian cells. This protein complex appears to be analogous to the COP9 complex in plants, which is important in light-mediated plant development. Although the specific function of JAB-1 in this complex is unclear, it has recently been implicated in targeting proteins for degradation by the proteasome.
TRUSTED_SUSTAINABILITY

Specifications

Antigen JAB1
Applications Immunoprecipitation, Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 8H8.5
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative; pH 7.4
Gene Cops5
Gene Accession No. O35864, Q92905
Gene Alias 38 kDa Mov34 homolog; AI303502; COP9 (constitutive photomorphogenic) homolog, subunit 5; COP9 (constitutive photomorphogenic) homolog, subunit 5 (Arabidopsis thaliana); COP9 complex S5; COP9 constitutive photomorphogenic homolog subunit 5; COP9 signalosome complex subunit 5; COP9 signalosome subunit 5; Cops5; CSN5; JAB1; Jun activation domain-binding protein 1; Jun coactivator; Kic2; Kip1 C-terminus-interacting protein 2; MGC3149; Mov34; MOV-34; SGN5; signalosome subunit 5; testis secretory sperm-binding protein Li 231m
Gene Symbols Cops5
Host Species Mouse
Immunogen The full-length mouse JAB-1 gene expressed in E. coli.
Purification Method Protein G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10987, 26754, 312916
Target Species Drosophila, Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG2a
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