Invitrogen™ JAM2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA521576

Catalog No. PIPA521576

Description

Recommended positive controls: A431, Neuro2A, GL261, C8D30, NIH-3T3, BCL-1, Raw264.7, C2C12. Predicted reactivity: Mouse (81%), Rat (81%), Bovine (90%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is localized in the tight junctions between high endothelial cells. It acts as an adhesive ligand for interacting with a variety of immune cell types and may play a role in lymphocyte homing to secondary lymphoid organs.

Specifications

• Antigen: JAM2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: JAM2
• Gene Alias: 1110002N23Rik; 2410030G21Rik; 2410167M24Rik; AU016127; C21orf43; CD322; Jam2; JAM-2; JAMB; JAM-B; JAM-IT/VE-JAM; Jcam2; junction adhesion molecule 2; junction adhesion molecule B; junction cell adhesion molecule 2; junctional adhesion molecule 2; Junctional adhesion molecule B; PRO245; RP23-253E17.2; UNQ219/PRO245; Vascular endothelial junction-associated molecule; VEJAM; VE-JAM
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 58494
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: P57087
• Gene Symbols: JAM2
• Immunogen: Recombinant fragment corresponding to a region within amino acids 1 and 294 of JAM-B (Uniprot ID#P57087).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov