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Invitrogen™ JMJD2B Recombinant Superclonal™ Antibody (9HCLC)

Catalog No. 712584
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71-258-4 100 μg
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Catalog No. 71-258-4 Supplier Invitrogen™ Supplier No. 712584
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Description

Rabbit Recombinant Superclonal Antibody

This antibody is predicted to react with Mouse, Rat, Bovine. Recombinant rabbit Superclonal™ antibodies are unique offerings from Thermo Fisher Scientific. They are comprised of a selection of multiple different recombinant monoclonal antibodies, providing the best of both worlds - the sensitivity of polyclonal antibodies with the specificity of monoclonal antibodies - all delivered with the consistency only found in a recombinant antibody. While functionally the same as a polyclonal antibody - recognizing multiple epitope sites on the target and producing higher detection sensitivity for low abundance targets - a recombinant rabbit Superclonal™ antibody has a known mixture of light and heavy chains. The exact population can be produced in every lot, circumventing the biological variability typically associated with polyclonal antibody production. Note: Formerly called 'Recombinant polyclonal antibody', this product is now rebranded as 'Recombinant Superclonal™ antibody'. The physical product and the performance remain unchanged.

Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Only able to demethylate trimethylated H3 'Lys-9', with a weaker activity than KDM4A, KDM4C and KDM4D. Demethylation of Lys residue generates formaldehyde and succinate. [UniProt].
TRUSTED_SUSTAINABILITY

Specifications

Antigen JMJD2B
Applications Western Blot
Classification Recombinant Superclonal
Clone 9HCLC
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.4
Gene KDM4B
Gene Accession No. O94953
Gene Alias 4732474L06Rik; JHDM3B; JmjC domain-containing histone demethylation protein 3B; Jmjd2b; jumonji domain containing 2B; jumonji domain-containing protein 2B; KDM4B; KIAA0876; lysine (K)-specific demethylase 4B; lysine demethylase 4B; lysine-specific demethylase 4B; mKIAA0876; TDRD14B; tudor domain containing 14B
Gene Symbols KDM4B
Host Species Rabbit
Immunogen Protein corresponding to human JMJD2B [aa1031-aa1096].
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23030
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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