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Invitrogen™ JMJD2C Monoclonal Antibody (OTI5B9)
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Catalog No. PIMA524956
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100 μL
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PIMA524956 100 μL
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Catalog No. PIMA524956 Supplier Invitrogen™ Supplier No. MA524956
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Description

Mouse Monoclonal Antibody

JMJD2C Monoclonal Antibody for Western Blot, IHC (P), ICC/IF

Jumonji domain-containing protein 2C (JMJD2C)/ Lysine-specific demethylase 4C (KDM4C) is a histone demethylase that specifically demethylates 'Lys-9' and 'Lys-36' residues of histone H3; thereby, playing a central role in histone code. KDM4C does not demethylate histone H3 'Lys-4', H3 'Lys-27', or H4 'Lys-20'. It demethylates trimethylated H3 'Lys-9' and H3 'Lys-36' residues. There is no activity on mono- or dimethylated residues. Demethylation of Lys residues generates formaldehyde and succinate.
TRUSTED_SUSTAINABILITY

Specifications

Antigen JMJD2C
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Monoclonal
Clone OTI5B9
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene KDM4C
Gene Accession No. Q9H3R0
Gene Alias 2410141F18Rik; AA517467; bA146B14.1; GASC1; GASC-1 protein; gene amplified in squamous cell carcinoma 1; gene amplified in squamous cell carcinoma 1 protein; JHDM3C; JmjC domain-containing histone demethylation protein 3C; JMJD2C; jumonji domain containing 2C; jumonji domain-containing protein 2C; Kdm4c; KIAA0780; lysine (K)-specific demethylase 4C; lysine demethylase 4C; lysine-specific demethylase 4C; RP11-169L18.1; TDRD14C; tudor domain containing 14C
Gene Symbols KDM4C
Host Species Mouse
Immunogen Full-length protein expressed in 293T cell transfected with human KDM4C expression vector.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23081
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
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