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  5. Tocris Bioscience™ JNJ 5207852 dihydrochloride

Tocris Bioscience™ JNJ 5207852 dihydrochloride
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Catalog No. 402050
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40-205-0 50 mg
40-201-0 10 mg
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Catalog No. 40-205-0 Supplier Tocris Bioscience™ Supplier No. 4020/50
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Description

High affinity H3 receptor antagonist

High affinity histamine H3 receptor neutral antagonist (pKi values are 8.9 and 9.2 in rat and human respectively). Brain penetrant and orally active. Has 3- and 100-fold higher affinity than thioperamide (Cat. No. 0644) for rat and human H3 receptors respectively. Suppresses slow-wave sleep; exhibits wake-promoting effects in rodent arousal models.

Chemical Identifiers

CAS 398473-34-2
Molecular Formula C20H32N2O

Specifications

Quantity 50 mg
Formula Weight 389.4
Purity >99%
Molecular Weight (g/mol) 316.489
Chemical Name or Material JNJ 5207852 dihydrochloride

Safety and Handling

Recommended Storage Desiccate at Room Temperature
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