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  5. Tocris Bioscience™ JNJ 5207852 dihydrochloride

Tocris Bioscience™ JNJ 5207852 dihydrochloride
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Catalog No. 402050
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

High affinity H3 receptor antagonist

High affinity histamine H3 receptor neutral antagonist (pKi values are 8.9 and 9.2 in rat and human respectively). Brain penetrant and orally active. Has 3- and 100-fold higher affinity than thioperamide (Cat. No. 0644) for rat and human H3 receptors respectively. Suppresses slow-wave sleep; exhibits wake-promoting effects in rodent arousal models.

Chemical Identifiers

CAS 398473-34-2
Molecular Formula C20H32N2O

Specifications

Quantity 50 mg
Formula Weight 389.4
Purity >99%
Molecular Weight (g/mol) 316.489
Chemical Name or Material JNJ 5207852 dihydrochloride

Safety and Handling

Recommended Storage Desiccate at Room Temperature
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