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Invitrogen™ JNK1 Polyclonal Antibody
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Catalog No. 44690G
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44-690-G 100 μL
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Catalog No. 44-690-G Supplier Invitrogen™ Supplier No. 44690G
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Description

Rabbit Polyclonal Antibody

JNK1 Polyclonal Antibody for IHC (P), Western Blot

MAPK8 (JNK1) is activated by the presence of misfolded proteins in the endoplasmic reticulum. It is also a crucial mediator of insulin resistance and obesity. It belongs to the MAPK superfamily of stress-activated protein kinases. MAPKs are Serine-threonine protein kinases that are activated in response to a variety of extracellular stimuli, and mediate signal transduction from the cell surface to the nucleus. JNK is involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. JNK pathways are activated by stress and inflammatory signals. JNK is expressed as ten different isoforms due to differential mRNA splicing. The predominant forms are JNK1 and JNK2.
TRUSTED_SUSTAINABILITY

Specifications

Antigen JNK1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation Dulbecco's PBS with 1mg/mL BSA and 0.05% sodium azide; pH 7.3
Gene MAPK8
Gene Accession No. P45983, P49185, Q91Y86
Gene Alias AI849689; c-Jun N-terminal kinase 1; FLJ12099; FLJ33785; JNK; JNK1; JNK1 beta1 protein kinase; jnk1a-1; JNK1A2; JNK21B1/2; JNK-46; JUN N-terminal kinase; MAP kinase 8; MAPK 8; Mapk8; mapk8 protein; mapk8b; MGC50974; mitogen activated protein kinase 8; mitogen-activated protein kinase 8; mitogen-activated protein kinase 8 isoform JNK1 alpha1; mitogen-activated protein kinase 8 isoform JNK1 beta2; mitogen-activated protein kinase 8b; OTTHUMP00000019552; p493F12; p54 gamma; p54bSAPK; PRKM8; protein kinase JNK1; protein kinase mitogen-activated 8; SAPK gamma; SAPK1; SAPK1C; stress-activated protein kinase 1; stress-activated protein kinase 1c; Stress-activated protein kinase JNK1; zgc:112379
Gene Symbols MAPK8
Host Species Rabbit
Immunogen The antiserum was produced against a chemically synthesized peptide derived from an internal region of JNK1. This region is conserved among human, mouse, and rat forms of JNK1, JNK2, and JNK3 proteins.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 116554, 26419, 5599
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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