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Eurofins Discoverx (+)-JQ1, 1 mg. (92-1149)

Supplier:  Eurofins Discoverx 921149

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JQ1 is a chemical compound which is under development as a non-hormonal male contraceptive drug. Its chemical structure is a triazolothienodiazepine, a series originally discovered by Mitsubishi Pharma [WO/2009/084693], related to benzodiazepine derivatives such as etizolam, however JQ1 does not produce sedative or anxiolytic effects and is instead a potent and selective inhibitor of the bromodomain testis-specific protein BRDT, which is essential for chromatin remodeling during spermatogenesis. Provided as 1 mg of dry powder. These highly purified, pre-validated control ligands have been used to qualify our InCELL Hunter,  PathHunter and cAMP Hunter cell lines as well as our Assay Ready Kits. Ligands are conveniently supplied with a recommended reconstitution buffer. For detailed information and product-specific datasheet, visit www.discoverx.com/ligands.

Catalog No. 50-199-9680


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