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Invitrogen™ JTB Polyclonal Antibody
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Catalog No. PIPA5103208
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100 μL
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PIPA5103208 100 μL
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Catalog No. PIPA5103208 Supplier Invitrogen™ Supplier No. PA5103208
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total JTB.

Required for normal cytokinesis during mitosis. Plays a role in the regulation of cell proliferation. May be a component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Increases AURKB activity. Inhibits apoptosis induced by TGFB1. Overexpression induces swelling of mitochondria and reduces mitochondrial membrane potential.
TRUSTED_SUSTAINABILITY

Specifications

Antigen JTB
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene JTB
Gene Accession No. O76095
Gene Alias hJT; HJTB; HSPC222; Jtb; jumping translocation breakpoint; jumping translocation breakpoint protein; PAR; PAR protein; Prostate androgen-regulated protein; protein JTB
Gene Symbols JTB
Host Species Rabbit
Immunogen A synthesized peptide derived from human JTB(Accession O76095), corresponding to amino acid residues R67-A117.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10899
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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