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AdipoGen K-252c

Supplier: AdipoGen AGCN20097M001

Chemical. CAS 85753-43-1. Formula C20H13N3O. MW 311.4. Isolated from Streptomyces longisporoflavus. Indolocarbazole alkaloid antibiotic. Potent cell permeable reversible and ATP-competitive PKC protein kinase C inhibitor with 10-fold selectivity over PKA protein kinase A. Anticancer compound. Cytotoxic againt various cancer cell lines. Apoptosis inducer. Antiviral compound against GCV-sensitive and -resistant strains of human cytomegalovirus HCMV. LACTB beta-lactamase, malate dehydrogenase MDH2, MDHC, MDH1B, ME1. ME2, ME3 and chymotrypsin inhibitor. Inhibits mixed lineage kinase MLK.
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