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Invitrogen™ K-Ras (G12A Mutant) Recombinant Rabbit Monoclonal Antibody (HL1153)
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Catalog No. PIMA546940
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PIMA546940 100 μL
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Catalog No. PIMA546940 Supplier Invitrogen™ Supplier No. MA546940
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Rabbit Recombinant Monoclonal Antibody

Store as concentrated solution. Centrifuge briefly prior to opening vial.

This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily A single amino acid substitution is responsible for an activating mutation The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region.
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Specifications

Antigen K-Ras (G12A Mutant)
Applications Western Blot
Classification Recombinant Monoclonal
Clone HL1153
Concentration 2 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative
Gene Accession No. P29466, P48729, Q8N752
Gene Alias ALPS4; C-BAS/HAS; CFC2; C-HA-RAS1; C-H-RAS; c-Ki-ras; c-Ki-ras2; c-K-ras; CMNS; CTLO; HAMSV; HRas proto-oncogene, GTPase; HRAS1; H-RASIDX; Ki-Ras; KRAS; K-Ras; KRAS proto-oncogene, GTPase; KRAS1; KRAS2; K-RAS2A; K-RAS2B; K-RAS4A; K-RAS4B; NCMS; N-ras; NRAS proto-oncogene, GTPase; NRAS1; NS; NS3; NS6; p21ras; RALD; RASH1; RASK2
Host Species Rabbit
Immunogen Carrier-protein conjugated synthetic peptide surrounding mutant G12A of human K-Ras. The exact sequence is proprietary.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 122011, 1452, 834
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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WARNING: Cancer - www.P65Warnings.ca.gov
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