KANK2/SIP Polyclonal Antibody, Bethyl Laboratories

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-156-0308	Bethyl Laboratories, Inc A301407AT	20 μL

Description

The recommended shelf life for this product is 1 year from date of receipt. Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

Ankyrins are membrane adaptor molecules that play important roles in the control of cytoskeleton formation by regulating actin polymerization. KANK2 (KN motif and ankyrin repeat domain-containing protein 2), was initially identified as a steroid receptor coactivator (SRC) interacting protein (SIP) that could sequester steroid receptor coactivators in the cytoplasm. More recent experiments have shown that while KANK2 is widely expressed, in kidney podocytes, KANK2 localizes to foot processes, suggesting that KANK2 may contribute to controlling actin dynamics in podocyte foot processes.

Specifications

• Antigen: KANK2/SIP
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: TBS with 0.1% BSA and 0.09% sodium azide
• Gene Alias: KANK2, KN motif and ankyrin repeat domains 2, SRC-interacting protein, SIP, matrix-remodeling-associated protein 3, MXRA3, Ankyrin repeat domain-containing protein 25, ANKRD25
• Gene Symbols: KANK2
• Isotype: IgG
• Purification Method: Antigen affinity chromatography
• Product Type: Antibody

• Applications: Immunohistochemistry, Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human
• Gene Accession No.: Q63ZY3
• Gene ID (Entrez): 25959
• Immunogen: Between 550 and 600
• Primary or Secondary: Primary
• Content And Storage: 4° C
• Gene: KANK2