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KANK2/SIP Rabbit anti-Human, Polyclonal, Bethyl Laboratories

Catalog No. 501560306
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50-156-0306 100 μL
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Catalog No. 50-156-0306 Supplier Bethyl Laboratories, Inc Supplier No. A301407A
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

Ankyrins are membrane adaptor molecules that play important roles in the control of cytoskeleton formation by regulating actin polymerization. KANK2 (KN motif and ankyrin repeat domain-containing protein 2), was initially identified as a steroid receptor coactivator (SRC) interacting protein (SIP) that could sequester steroid receptor coactivators in the cytoplasm. More recent experiments have shown that while KANK2 is widely expressed, in kidney podocytes, KANK2 localizes to foot processes, suggesting that KANK2 may contribute to controlling actin dynamics in podocyte foot processes.

Specifications

Antigen KANK2/SIP
Applications Immunohistochemistry, Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 1 mg/ml
Conjugate Unconjugated
Formulation phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene KANK2
Gene Accession No. Q63ZY3
Gene Alias KANK2, KN motif and ankyrin repeat domains 2, SRC-interacting protein, SIP, matrix-remodeling-associated protein 3, MXRA3, Ankyrin repeat domain-containing protein 25, ANKRD25
Gene Symbols KANK2
Host Species Rabbit
Immunogen Between 550 and 600
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 25959
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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