Invitrogen™ KANK3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA562333

Catalog No. PIPA562333

Description

Immunogen sequence: QLREATTQTP WSCAEKAAQT ESPAEAPSLT QESSPGSMDG DRAVAPAGIL KSIMK Highest antigen sequence identity to the following orthologs: Mouse - 45%, Rat - 51%.

Ankyrins are membrane adaptor molecules that play important roles in the control of cytoskeleton formation by regulating actin polymerization. Like other members of the KANK family, KANK3 (KN motif and ankyrin repeat domain-containing protein 3), is thought to play a role in the formation of actin stress fibers. In zebrafish, the homolog of KANK3 interacts with the adaptor protein Numb, a protein implicated in multiple basic cellular processes, and is essential for epidermal integrity and neurulation, suggesting that KANK3 may play a similar role in higher organisms.

Specifications

• Antigen: KANK3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: KANK3
• Gene Alias: 0610013D04Rik; Ankrd47; ankyrin repeat domain 47; ankyrin repeat domain-containing protein 47; D17Ertd288e; Kank3; kidney ankyrin repeat-containing protein 3; KN motif and ankyrin repeat domain-containing protein 3; KN motif and ankyrin repeat domains 3; NG28; putative KN motif and ankyrin repeat domains 3
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 256949
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q6NY19
• Gene Symbols: KANK3
• Immunogen: Recombinant protein corresponding to Human KANK3. Recombinant protein control fragment (Product #RP-99982).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov