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Invitrogen™ Kappa Light Chain Monoclonal Antibody (A8H10)
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Catalog No. FEMA550617
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100 μL
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Catalog No. Quantity
FEMA550617 100 μL
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Catalog No. FEMA550617 Supplier Invitrogen™ Supplier No. MA550617
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Description

Mouse Monoclonal Antibody

Positive control: Human tonsil tissue, human appendix tissue. Predicted band size: 11.7 kDa Subcellular Location: Cell membrane, Secreted.

Immunoglobulin classes share the same basic four polypeptide chain structure of two heavy chains (five types) and two light chains (kappa, lambda; both having a molecular weight of 22.5 kDa). Kappa and lambda consist of a variable region and a constant region and can easily be differentiated by the antigenic properties of the constant region. The ratio of kappa to lambda is 70:30. Antibodies to the kappa light chain are reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Kappa Light Chain
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone A8H10
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene IGK
Gene Accession No. P01601, P01602, P01834, P0DOX7
Gene Alias D4Mit8; HCAK1; ig kappa chain c region; Igk; Igk@; Igkc; Igk-C; IGKCD; IGKV; IGKV15; IGKV1-5; Immunoglobulin K; immunoglobulin kappa chain complex; immunoglobulin kappa constant; immunoglobulin kappa light chain; immunoglobulin kappa locus; immunoglobulin kappa variable 1-5; kappa; Kappa LC; Km; L12; L12a; LOC500183; similar to NGF-binding Ig light chain; V1
Gene Symbols IGK, IGKC, IGKV1-5, IGKV1D-16
Host Species Mouse
Immunogen Recombinant full protein within human Kappa Light Chain.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 28299, 28901, 3514, 50802
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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