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Invitrogen™ KappaB ras1 Monoclonal Antibody (184C278)
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Catalog No. 01676586
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100 μg
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Catalog No. Quantity
01-676-586 100 μg
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Catalog No. 01-676-586 Supplier Invitrogen™ Supplier No. MA141180
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Description

Mouse Monoclonal Antibody

Suggested positive control: 293 whole cell lysate. Immunogen sequence: RVELLKKEID KFKDKKEV.

KappaB ras-1 (kappa-B-ras-1) and kappaB-ras-2 are two small proteins that similar to Ras-like small GTPases that associate with Ikappa-B (Ikappa-B), an inhibitor of the transcription factor NF-kappa-B. Ikappa-B exists in two homologous forms, Ikappa-B-alpha and Ikappa-B-beta, although Ikappa-B-beta contains a unique 47-amino acid region within its ankyrin domain. While inactive Ikappa-B-alpha-NF-kappa-B complexes can shuttle in and out of the nucleus, Ikappa-B-beta-NF-kappa-B complexes are retained exclusively in the cytoplasm. It is suggested that kappaB-ras proteins preferentially bind to the Ikappa-B-beta form through this unique insert within the ankyrin region, thus modulating the cellular location of Ikappa-B-beta and regulating the rate of degradation of Ikappa-B-beta.
TRUSTED_SUSTAINABILITY

Specifications

Antigen KappaB ras1
Applications Western Blot
Classification Monoclonal
Clone 184C278
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.2% gelatin and 0.05% sodium azide
Gene NKIRAS1
Gene Accession No. Q8CEC5, Q9NYS0
Gene Alias 2400004O09Rik; C15orf1; I1PP2A; I-kappa-B-interacting Ras-like protein 1; kappa B-ras 1; kappa B-Ras protein 1; kappaB-Ras1; KBRAS1; LANP; MAPM; MGC119787; MGC150373; NF-kappa-B inhibitor-interacting Ras-like protein 1; NFKB inhibitor interacting Ras like 1; NFKB inhibitor interacting Ras-like 1; NFKB inhibitor interacting Ras-like 1 S homeolog; NFKB inhibitor interacting Ras-like protein 1; Nkiras1; nkiras1.S; PHAP1; PHAPI; PP32; XELAEV_18033117mg
Gene Symbols NKIRAS1, nkiras1.S
Host Species Mouse
Immunogen Synthetic peptide containing amino acid residues 96-113 of human kB-Ras1.
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100036787, 100051752, 100620195, 28512, 305751, 477047, 522875, 69721
Target Species Human, Mouse, Rat, Canine, Monkey, Bovine, Pig, Horse, Frog
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1 κ
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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