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Invitrogen™ KChIP2 Polyclonal Antibody
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Catalog No. PIPA541075
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100 μL
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PIPA541075 100 μL
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Catalog No. PIPA541075 Supplier Invitrogen™ Supplier No. PA541075
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Description

Rabbit Polyclonal Antibody

Peptide sequence: QLTDSVDDEF ELSTVCHRPE GLEQLQEQTK FTRKELQVLY RGFKNPGALS Sequence homology: Cow: 100%; Dog: 86%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%.

Voltage-gated potassium (Kv) channels are key components of the potassium currents in the heart and central nervous system. In the heart, Kv4 channels are involved in the repolarization phase of the action potential. In the brain however, these channels prevent reverse-propagation of action potentials. Found associated with Kv4 channels are a group of calcium-binding proteins termed KChIPs (Kv channel interacting proteins). KChIPs are small molecular weight proteins that bind to the cytoplasmic amino termini of Kv4 alpha-subunits and help to modulate its function. There are currently three known KChIPs; KChIP1 expressed in the brain; KChIP2 expressed in the brain, heart, and lung, and has three isoforms, a, b, and c; and KChIP3, also known as calsenilin and DREAM (downstream regulatory elements (DRE)-antagonist modulator) which is expressed in the brain and testis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen KChIP2
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene KCNIP2
Gene Accession No. Q9JJ69, Q9NS61
Gene Alias A-type potassium channel modulatory protein 2; Cardiac voltage-gated potassium channel modulatory subunit; DKFZp566L1246; KCHIP2; KChlP2; Kcnip2; Kv channel interacting protein 2; Kv channel-interacting protein; Kv channel-interacting protein 2; MGC17241; potassium channel auxiliary subunit KCHIP2; potassium channel-interacting protein 2; potassium voltage-gated channel interacting protein 2; si:ch73-173h19.2
Gene Symbols KCNIP2
Host Species Rabbit
Immunogen Synthetic peptide directed towards the N-terminal of human KCNIP2.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 30819, 80906
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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