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Invitrogen™ KCNH1 Polyclonal Antibody
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Catalog No. PIPA553989
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100 μL
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PIPA553989 100 μL
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Catalog No. PIPA553989 Supplier Invitrogen™ Supplier No. PA553989
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: DSCDSGITKS DLRLDNVGEA RSPQDRSPIL AEVKHSFYPI PEQTLQATVL EVRHELKEDI KALNAKMTNI EKQLSEILRI LTSRRSSQSP QELFEISRPQ SPES Highest antigen sequence identity to the following orthologs: Mouse - 91%, Rat - 92%.

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. KCNH1 encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit of a voltage-gated non-inactivating delayed rectifier potassium channel. KCNH1 is activated at the onset of myoblast differentiation. KCNH1 is highly expressed in brain and in myoblasts. Overexpression of KCNH1 may confer a growth advantage to cancer cells and favor tumor cell proliferation. Alternative splicing of KCNH1 results in two transcript variants encoding distinct isoforms.
TRUSTED_SUSTAINABILITY

Specifications

Antigen KCNH1
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.6 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene KCNH1
Gene Accession No. O95259
Gene Alias EAG; EAG channel 1; EAG1; ether a go-go; ether-a-go-go potassium channel 1; ether-a-go-go, Drosophila, homolog of; h-eag; hEAG1; Kcnh1; Kv10.1; M-eag; potassium channel, voltage gated eag related subfamily H, member 1; potassium voltage-gated channel subfamily H member 1; potassium voltage-gated channel, subfamily H (eag-related), member 1; r-eag; TMBTS; voltage-gated potassium channel subunit Kv10.1; ZLS1
Gene Symbols KCNH1
Host Species Rabbit
Immunogen Recombinant protein fragment of Human KCNH1 (Product #RP-91156)
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3756
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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