KCNIP2 Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Supplier:  Proteintech Group Inc 201921AP150UL

Catalog No. 50-173-2760

Description

This antibody can recognize the 31 kDa and 29 kDa isoforms.

Voltage-gated potassium (Kv) channels are key components of the potassium currents in the heart and central nervous system. In the heart, Kv4 channels are involved in the repolarization phase of the action potential. In the brain however, these channels prevent reverse-propagation of action potentials. Found associated with Kv4 channels are a group of calcium-binding proteins termed KChIPs (Kv channel interacting proteins). KChIPs are small molecular weight proteins that bind to the cytoplasmic amino termini of Kv4 alpha-subunits and help to modulate its function. There are currently three known KChIPs; KChIP1 expressed in the brain; KChIP2 expressed in the brain, heart, and lung, and has three isoforms, a, b, and c; and KChIP3, also known as calsenilin and DREAM (downstream regulatory elements (DRE)-antagonist modulator) which is expressed in the brain and testis.

Specifications

• Antigen: KCNIP2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: KCNIP2
• Gene Alias: KCHIP2, KCNIP2
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 30819, 80906
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.47 mg/mL
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Accession No.: Q9JJ69, Q9NS61
• Gene Symbols: KCNIP2
• Immunogen: KCNIP2 Fusion Protein Ag14111
• Quantity: 150 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG