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KCNIP2 Rabbit anti-Human, Mouse, Polyclonal, Proteintech
SDP

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group Inc 201921AP150UL

Encompass_Preferred

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Catalog No. 50-173-2760


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Description

Description

This antibody can recognize the 31 kDa and 29 kDa isoforms.

Voltage-gated potassium (Kv) channels are key components of the potassium currents in the heart and central nervous system. In the heart, Kv4 channels are involved in the repolarization phase of the action potential. In the brain however, these channels prevent reverse-propagation of action potentials. Found associated with Kv4 channels are a group of calcium-binding proteins termed KChIPs (Kv channel interacting proteins). KChIPs are small molecular weight proteins that bind to the cytoplasmic amino termini of Kv4 alpha-subunits and help to modulate its function. There are currently three known KChIPs; KChIP1 expressed in the brain; KChIP2 expressed in the brain, heart, and lung, and has three isoforms, a, b, and c; and KChIP3, also known as calsenilin and DREAM (downstream regulatory elements (DRE)-antagonist modulator) which is expressed in the brain and testis.
Specifications

Specifications

KCNIP2
Polyclonal
Unconjugated
KCNIP2
KCHIP2, KCNIP2
Rabbit
Antigen Affinity Chromatography
RUO
30819, 80906
-20°C
Liquid
Western Blot
0.47 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q9JJ69, Q9NS61
KCNIP2
KCNIP2 Fusion Protein Ag14111
150 μL
Primary
Human, Mouse
Antibody
IgG
SDS
Documents
Product Certifications
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