KCNK18 Rabbit anti-Human, Polyclonal, Proteintech

Catalog No.	Quantity
50-173-4109	150 μL

Catalog No. 50-173-4109 Supplier Proteintech Group Inc Supplier No. 237121AP150UL

Description

Rabbit Polyclonal Antibody

This antibody can be used to detect endogenous KCNK18, however, the reason for the additional band of 130-140 kDa is still unknown.

TRESK (TWIK-related spinal cord K+ channel) is a two-pore domain K+ channel that induces outward rectification and functions as a background K+ channel that is abundantly expressed in the spinal cord, thymus, spleen, and leukemic T-lymphocytes. TRESK is activated by increased cytoplasmic calcium concentration through calcineurin as well as by acetylcholine and histamine. It has been suggested that TRESK is linked to acute and chronic pain by activation of calcineurin. Other studies indicate that TRESK may play a role in the regulation of T-cell function and could be an excellent target to treat T-cell originated immune dysfunction.

Specifications

• Antigen: KCNK18
• Applications: Immunocytochemistry, Immunofluorescence, Western Blot
• Classification: Polyclonal
• Concentration: 0.45 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene: KCNK18
• Gene Accession No.: Q7Z418
• Gene Alias: K2p18.1, KCNK18, TRESK, TRESK 2, TRESK2, TRIK
• Gene Symbols: KCNK18
• Host Species: Rabbit
• Immunogen: KCNK18 Fusion Protein Ag20514
• Purification Method: Antigen Affinity Chromatography
• Quantity: 150 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 338567
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG