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Invitrogen™ KCNN3 Polyclonal Antibody
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Catalog No. PIPA596511
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100 μL
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PIPA596511 100 μL
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Catalog No. PIPA596511 Supplier Invitrogen™ Supplier No. PA596511
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: VARKLELTKA EKHVHNFMMD TQLTKRIKNA AANVLRETWL IYKHTKLLKK IDHAKVRKHQ RKFLQAIHQL RSVKMEQRKL SDQANTLVDL SKMQNVMYDL ITELNDRSED LEKQIGSLES KLEHLTASFN SLPLLIADTL RQQQQQLLSA IIEARGVSVA VGTTHTPISD SPIGVSSTSF PTPYTSSSSC; Positive Samples: NCI-H460; Cellular Location: Membrane, Multi-pass membrane protein.

Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. KCNN3, a member of the KCNN family of potassium channel genes, encodes a protein that is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits.
TRUSTED_SUSTAINABILITY

Specifications

Antigen KCNN3
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.16 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene KCNN3
Gene Accession No. Q9UGI6
Gene Alias hSK3; K3; KCa2.3; Kcnn3; potassium calcium-activated channel subfamily N member 3; potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 3; potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3; SK3; SKCa 3; SKCa3; small conductance calcium-activated potassium channel 3; small conductance calcium-activated potassium channel protein 3; small-conductance Ca2+-activated K+ channel 3
Gene Symbols KCNN3
Host Species Rabbit
Immunogen Recombinant protein (or fragment)
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3782
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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