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Invitrogen™ KCNN3 Polyclonal Antibody
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Catalog No. PIPA5115457
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100 μL
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PIPA5115457 100 μL
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Catalog No. PIPA5115457 Supplier Invitrogen™ Supplier No. PA5115457
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total KCNN3.

Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. KCNN3, a member of the KCNN family of potassium channel genes, encodes a protein that is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits.
TRUSTED_SUSTAINABILITY

Specifications

Antigen KCNN3
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide
Gene KCNN3
Gene Accession No. P58391, P70605, Q9UGI6
Gene Alias hSK3; K3; KCa2.3; Kcnn3; potassium calcium-activated channel subfamily N member 3; potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 3; potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3; SK3; SKCa 3; SKCa3; small conductance calcium-activated potassium channel 3; small conductance calcium-activated potassium channel protein 3; small-conductance Ca2+-activated K+ channel 3
Gene Symbols KCNN3
Host Species Rabbit
Immunogen A synthesized peptide derived from human KCNN3(Accession Q9UGI6), corresponding to amino acid residues M1-Q33.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 140493, 3782, 54263
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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