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  6. KCNQ2 Mouse anti-Human, Mouse, Porcine, Rat, Clone: 1D4A1, Proteintech 

KCNQ2 Mouse anti-Human, Mouse, Porcine, Rat, Clone: 1D4A1, Proteintech
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Catalog No. 501737179 Shop All Proteintech Group Inc Products
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50-173-7179 150 μL
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Catalog No. 50-173-7179 Supplier Proteintech Group Inc Supplier No. 667741IG150UL
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Description

Mouse Monoclonal Antibody

KCNQs are members of the voltage-dependent non-inactivating potassium channel family. Currently there are five known KNCQs (KCNQ1-5) found in the central nervous system and KNCQ2 and 3 have demonstrated their importance in M-current activation. Studies have shown that KCNQ2 and KCNQ3 form heteromultimers that, when formed, substantially increase the M-current. Inhibition of M-current controls neuron excitability throughout the nervous system as well as the responsiveness to synaptic inputs. Genetic mutations in these proteins have been linked to disorders such as benign familial neonatal convulsions (BFNC), deafness, neuropathic pain and epilepsy.

Specifications

Antigen KCNQ2
Applications Western Blot
Classification Monoclonal
Clone 1D4A1
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene KCNQ2
Gene Accession No. O43526, O88943, Q9Z351
Gene Alias BFNC, EBN, EBN1, ENB1, HNSPC, KCNA11, KCNQ2, KQT like 2, KV7.2, KVEBN1
Gene Symbols Kcnq2
Host Species Mouse
Immunogen KCNQ2 Fusion Protein Ag25781
Purification Method Protein G
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 110257402, 16536, 170848, 3785
Target Species Human, Mouse, Pig, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG1
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