KCNQ2 Mouse anti-Human, Mouse, Porcine, Rat, Clone: 1D4A1, Proteintech

Mouse Monoclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-173-7179	Proteintech Group Inc 667741IG150UL	150 μL

Description

KCNQs are members of the voltage-dependent non-inactivating potassium channel family. Currently there are five known KNCQs (KCNQ1-5) found in the central nervous system and KNCQ2 and 3 have demonstrated their importance in M-current activation. Studies have shown that KCNQ2 and KCNQ3 form heteromultimers that, when formed, substantially increase the M-current. Inhibition of M-current controls neuron excitability throughout the nervous system as well as the responsiveness to synaptic inputs. Genetic mutations in these proteins have been linked to disorders such as benign familial neonatal convulsions (BFNC), deafness, neuropathic pain and epilepsy.

Specifications

• Antigen: KCNQ2
• Concentration: 1 mg/mL
• Classification: Monoclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Alias: BFNC, EBN, EBN1, ENB1, HNSPC, KCNA11, KCNQ2, KQT like 2, KV7.2, KVEBN1
• Gene Symbols: Kcnq2
• Isotype: IgG1
• Purification Method: Protein G
• Product Type: Antibody

• Clone: 1D4A1
• Applications: Western Blot
• Conjugate: Unconjugated
• Host Species: Mouse
• Target Species: Human, Mouse, Pig, Rat
• Gene Accession No.: O43526, O88943, Q9Z351
• Gene ID (Entrez): 110257402, 16536, 170848, 3785
• Immunogen: KCNQ2 Fusion Protein Ag25781
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: KCNQ2