KDM4C Polyclonal Antibody, Active Motif™

Rabbit Polyclonal Antibody

Supplier:  Active Motif 61688

Catalog No. 50-199-3619

Description

Jumonji domain-containing protein 2C (JMJD2C)/ Lysine-specific demethylase 4C (KDM4C) is a histone demethylase that specifically demethylates 'Lys-9' and 'Lys-36' residues of histone H3; thereby, playing a central role in histone code. KDM4C does not demethylate histone H3 'Lys-4', H3 'Lys-27', or H4 'Lys-20'. It demethylates trimethylated H3 'Lys-9' and H3 'Lys-36' residues. There is no activity on mono- or dimethylated residues. Demethylation of Lys residues generates formaldehyde and succinate.

Specifications

• Antigen: KDM4C
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene Alias: 2410141F18Rik; AA517467; bA146B14.1; GASC1; GASC-1 protein; gene amplified in squamous cell carcinoma 1; Gene amplified in squamous cell carcinoma 1 protein; JHDM3C; JmjC domain-containing histone demethylation protein 3C; Jmjd2c; jumonji domain containing 2C; Jumonji domain-containing protein 2C; KDM4C; KIAA0780; lysine (K)-specific demethylase 4C; lysine demethylase 4C; Lysine-specific demethylase 4C; RP11-169L18.1; TDRD14C; tudor domain containing 14C
• Immunogen: This antibody was raised against a peptide within human kDM4C.
• Quantity: 10 μL
• Primary or Secondary: Primary
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: Lot-Specific
• Formulation: PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Target Species: Monkey
• Product Type: Antibody
• Isotype: IgG