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Invitrogen™ KDM5B Monoclonal Antibody (7H3D7)
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Catalog No. PIMA531785
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100 μL
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Catalog No. Quantity
PIMA531785 100 μL
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Catalog No. PIMA531785 Supplier Invitrogen™ Supplier No. MA531785
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Description

Mouse Monoclonal Antibody

MA5-31785 has been tested in indirect ELISA.

KDM5B is a histone demethylase that demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. It does not demethylate histone H3 'Lys-9' or H3 'Lys-27'. KDM5B demethylates trimethylated, dimethylated and monomethylated H3 'Lys-4'. It acts as a transcriptional corepressor for FOXG1B and PAX9. It favors the proliferation of breast cancer cells by repressing tumor suppressor genes such as BRCA1 and HOXA5. In contrast, KDM5B may act as a tumor suppressor for melanoma.
TRUSTED_SUSTAINABILITY

Specifications

Antigen KDM5B
Applications ELISA, Flow Cytometry, Western Blot
Classification Monoclonal
Clone 7H3D7
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% sodium azide
Gene KDM5B
Gene Accession No. Q9UGL1
Gene Alias 2010009J12Rik; 2210016I17Rik; AW556288; cancer/testis antigen 31; CT31; D1Ertd202e; Histone demethylase JARID1B; Jarid1b; jumonji, AT rich interactive domain 1B; jumonji, AT rich interactive domain 1B (Rbp2 like); Jumonji, AT rich interactive domain 1B (RBP2-like); jumonji/ARID domain-containing protein 1B; KDM5B; Kiaa4034; lysine (K)-specific demethylase 5B; lysine demethylase 5B; lysine-specific demethylase 5B; mKIAA4034; PLU1; PLU-1; PPP1R98; protein phosphatase 1, regulatory subunit 98; PUT1; putative DNA/chromatin binding motif; putative DNA/chromatin binding motif 1; Rb-Bp2; RBBP2H1; RBBP2H1A; RBP2-H1; Retinoblastoma-binding protein 2 homolog 1; retinoblastoma-binding protein 2, homolog 1A; RGD1565602
Gene Symbols KDM5B
Host Species Mouse
Immunogen Purified recombinant fragment of human KDM5B (AA: 231-319) expressed in E. coli.
Purification Method Protein G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10765
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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