Ketoconazole, 98%

Description

Potent inhibitor of cytochrome P450c17 | CAS: 65277-42-1 | C26H28Cl2N4O4 | 534.452 g/mol

Ketoconazole is used to treat candidiasis, chronic mucocutaneous candidiasis, oral thrush, candiduria, blastomycosis, coccidioidomycosis, histoplasmosis, chromomycosis, and paracoccidioidomycosis. Ketoconazole is an antifungal agent.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Ketoconazole is used to treat candidiasis, chronic mucocutaneous candidiasis, oral thrush, candiduria, blastomycosis, coccidioidomycosis, histoplasmosis, chromomycosis, and paracoccidioidomycosis. Ketoconazole is an antifungal agent.

Solubility
Soluble in DMSO, ethanol, chloroform, water, and methanol.

Notes
Store away from strong oxidizing agents. Keep container tightly closed. Store in cool, dry conditions in well sealed containers.

Specifications

Chemical Identifiers

• CAS: 65277-42-1
• Molecular Formula: C26H28Cl2N4O4
• Molecular Weight (g/mol): 534.452
• MDL Number: MFCD00058579
• InChI Key: XMAYWYJOQHXEEK-SIULDFEJSA-N
• Synonym: ketoconazole
• PubChem CID: 76973198
• IUPAC Name: 2,2,2-trideuterio-1-[4-[4-[[(2R,4S)-2-(2,4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazin-1-yl]ethanone
• SMILES: CC(=O)N1CCN(CC1)C2=CC=C(C=C2)OCC3COC(O3)(CN4C=CN=C4)C5=C(C=C(C=C5)Cl)Cl

• Color: White
• Quantity: 25 g
• UN Number: UN2811
• Merck Index: 14,5302
• Solubility Information: Soluble in DMSO,ethanol,chloroform,water,and methanol.
• Formula Weight: 531.43
• Percent Purity: 98%
• Physical Form: Powder
• Chemical Name or Material: Ketoconazole

Safety and Handling

Hazard Category	H301-H360F-H373
Hazard Statement	GHS H Statement H301-H360-H373 Toxic if swallowed. May damage fertility or the unborn child. May cause damage to organs through prolonged or repeated exposure.
Precautionary Statement	P201-P202-P260-P264b-P270-P281-P301+P310-P308+P313-P330-P501c
DOTInformation	Transport Hazard Class: 6.1; Packing Group: III; Proper Shipping Name: TOXIC SOLIDS, ORGANIC, N.O.S.
EINECSNumber	265-667-4
RTECSNumber	TK7912300
TSCA	No
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only