Ketoconazole, USP, 98-102%, Spectrum™ Chemical

Description

K1149, 65277-42-1, C₂₆H₂₈Cl₂N₄O₄

Spectrum™ Chemical Ketoconazole, USP is a synthetic antifungal medication that is used primarily to treat fungal infections. While its use as an oral tablet has been discontinued in many countries due to concerns that it caused serious liver injury, it is still used in a variety of topical administrations such as creams, which are used to treat tinea, candidal paronychia, and pityriasis versicolor and in shampoos used primarily to treat seborrheic dermatitis (dandruff). The USP grade indicates it is graded suitable for personal care, cosmetic and pharmaceutical applications. All Spectrum Chemical USP grade products are manufactured, packaged and stored under current Good Manufacturing Practices (cGMP) per 21CFR part 211 in FDA registered and inspected facilities.

Specifications

Chemical Identifiers

• CAS: 65277-42-1
• Molecular Formula: C26H28Cl2N4O4
• Molecular Weight (g/mol): 531.43
• InChI Key: XMAYWYJOQHXEEK-ZEQKJWHPSA-N
• IUPAC Name: 1-[4-(4-{[(2S,4R)-2-(2,4-dichlorophenyl)-2-[(1H-imidazol-1-yl)methyl]-1,3-dioxolan-4-yl]methoxy}phenyl)piperazin-1-yl]ethan-1-one
• SMILES: CC(=O)N1CCN(CC1)C1=CC=C(OC[C@@H]2CO[C@](CN3C=CN=C3)(O2)C2=CC=C(Cl)C=C2Cl)C=C1

• CAS Max %: 100%
• Ignition Residue: 0.1%
• Loss on Drying: 0.5%
• Packaging: Amber Glass Bottle
• Quantity: 5 g
• UN Number: UN2811
• Specific Rotation: -1° to +1°
• Percent Purity: 98 to 102%
• Grade: USP