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  5. Tocris Bioscience™ KG 5

Tocris Bioscience™ KG 5
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Catalog No. 526050
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Catalog No. Quantity
52-605-0 50 mg
52-601-0 10 mg
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Catalog No. 52-605-0 Supplier Tocris Bioscience™ Supplier No. 5260/50
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Description

PDGFRβ, B-Raf, c-Raf, FLT3 and KIT inhibitor

KG 5 is a PDGFRβ and B-Raf allosteric inhibitor. Also inhibits c-Raf, FLT3 and KIT. Disrupts blood vessel formation in zebrafish embryos and inhibits angiogenesis in a mouse angiogenesis model. Inhibits growth of renal and pancreatic tumors in mice. Also arrests cells in prometaphase. Orally available.

Specifications

Chemical Name or Material 2-(Methylthio)-6-[4-[5-[[3-(trifluoromethyl)phenyl]amino]-1H-1,2,4-triazol-3-yl]phenoxy]-4-pyrimidinamine
CAS 877874-85-6
Quantity 50 mg
Target Raf Kinase Inhibitors
Molecular Formula C20H16F3N7OS
Formula Weight 459.45
Purity >98%
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