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  5. Ki 16425

Ki 16425

Catalog No. 50565
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Quantity:
5 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

LPA1 and LPA3 receptor antagonist

Ki 16425 is an antagonist of the lysophosphatidic acid receptors LPA1 and LPA3 (Ki values are 0.25 and 0.36 μM respectively, in a GTPγS binding assay). Blocks LPA-induced dephosphorylation of Yes-associated protein (YAP) and WW domain-containing transcription regulator protein 1 (TAZ), inhibiting the Hippo signaling pathway, in HEK293A cells.

Specifications

Chemical Name or Material 3-[[[4-[4-[[[1-(2-Chlorophenyl)ethoxy]carbonyl]amino]-3-methyl-5-isoxazolyl]phenyl]methyl]thio]propanoic acid
CAS 355025-24-0
Assay Percent Range >98%
Quantity 5 mg
Molecular Formula C23H23ClN2O5S
Formula Weight Observed MW: 474.96
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