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  5. Ki 16425

Ki 16425

Catalog No. 50565
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Catalog No. Quantity
50-565 5 mg
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Catalog No. 50-565 Supplier R&D Systems Supplier No. 5056/5
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Description

LPA1 and LPA3 receptor antagonist

Ki 16425 is an antagonist of the lysophosphatidic acid receptors LPA1 and LPA3 (Ki values are 0.25 and 0.36 μM respectively, in a GTPγS binding assay). Blocks LPA-induced dephosphorylation of Yes-associated protein (YAP) and WW domain-containing transcription regulator protein 1 (TAZ), inhibiting the Hippo signaling pathway, in HEK293A cells.

Specifications

Chemical Name or Material 3-[[[4-[4-[[[1-(2-Chlorophenyl)ethoxy]carbonyl]amino]-3-methyl-5-isoxazolyl]phenyl]methyl]thio]propanoic acid
CAS 355025-24-0
Assay Percent Range >98%
Quantity 5 mg
Molecular Formula C23H23ClN2O5S
Formula Weight Observed MW: 474.96
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