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  6. Invitrogen™ Ki-67 Monoclonal Antibody (SolA15), Brilliant Ultra Violet™ 563, eBioscience™, Invitrogen™ 

Invitrogen™ Ki-67 Monoclonal Antibody (SolA15), Brilliant Ultra Violet™ 563, eBioscience™, Invitrogen™
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Catalog No. 365569882
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36-556-9882 100 μg
36-556-9880 25 μg
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Description

Rat Monoclonal Antibody

Ki-67 is a nuclear protein that is expressed during various stages in the cell cycle, particularly during late G1, S, G2, and M phases. The protein has a forkhead associated domain (FHA) through which it associates with euchromatin at the perichromosomal layer, the centromeric heterochromatin, and the nucleolus. Ki-67 is shown to have a cell cycle dependent topographical distribution with perinucleolar expression at G1, expression in the nuclear matrix at G2, and expression on the chromosomes during M phase. Ki-67 is commonly used as a proliferation marker because it is not detected in G0 cells, but increases steadily from G1 through mitosis. Ki-67 antibodies are useful in establishing the cell growing fraction in neoplasms. In neoplastic tissues, the prognostic value is comparable to the tritiated thymidine-labelling index. The correlation between low Ki-67 index and histologically low-grade tumors is strong. Ki-67 is routinely used as a neuronal marker of cell cycling and proliferation.
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Specifications

Antigen Ki-67
Applications Flow Cytometry
Classification Monoclonal
Clone SolA15
Concentration 0.2 mg/mL
Conjugate Brilliant Ultraviolet 563
Formulation PBS with BSA and 0.09% sodium azide; pH 7.2
Gene Mki67
Gene Accession No. E9PVX6, P46013
Gene Alias antigen identified by monoclonal antibody Ki 67; antigen identified by monoclonal antibody Ki-67; Antigen identified by monoclonal antibody Ki-67 homolog; Antigen KI-67; Antigen KI-67 homolog; antigen KI-67; proliferation marker protein Ki-67; antigen KI-67-like; cb31; D630048A14Rik; I79_022666; Ki67; Ki-67; KIA; LOW QUALITY PROTEIN: proliferation marker protein Ki-67; marker of proliferation Ki-67; MIB-; MIB-1; Mki67; PPP1R105; Proliferation marker protein Ki-67; proliferation-related Ki-67 antigen; protein phosphatase 1, regulatory subunit 105; RP11-380J17.2; sb:cb31; si:ch211-250b22.7; unnamed protein product; wu:fa11g09; wu:fb57a07; wu:fi14e05
Gene Symbols Mki67
Host Species Rat
Purification Method Affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100686578, 102135895, 17345, 291234, 4288
Target Species Canine, Cynomolgus Monkey, Human, Mouse, Monkey, Rat
Content And Storage 4°C, store in dark, DO NOT FREEZE!
Product Type Antibody
Form Liquid
Isotype IgG2a κ
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