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Tocris Bioscience™ Kifunensine
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Catalog No. 32071
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32-071 1 mg
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Catalog No. 32-071 Supplier Tocris Bioscience™ Supplier No. 3207/1
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Description

Inhibitor of class I α-mannosidases

Kifunensine is an inhibitor of class I α-mannosidases that inhibits glycoprotein processing. Kifunensine inhibits human endoplasmic reticulum α-1,2-mannosidase I and Golgi Class I mannosidases IA, IB and IC with Ki values of 130 and 23 nM respectively. Kifunensine disrupts normal trafficking of the GLUT1 transporter, leading to decreased glucose uptake in human renal epithelial cells. Kifunensine impaires tumour cell aggregation in human ovarian cancer cells in vitro.

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Chemical Identifiers

CAS 109944-15-2
Molecular Formula C8H12N2O6

Specifications

Quantity 1 mg
Formula Weight 232.19
Purity >98%
Molecular Weight (g/mol) 232.192
Chemical Name or Material Kifunensine

Safety and Handling

Recommended Storage Store at -20°C
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