Thermo Scientific™ Kinase Tracer 178, 25 μM

Description

In the LanthaScreen™ Eu Kinase Binding Assay, binding of an Alexa Fluor™ conjugate or tracer such as Kinase Tracer 178 to a kinase is detected by addition of a Eu-labeled anti-tag antibody.

In the LanthaScreen™ Eu Kinase Binding Assay, binding of an Alexa Fluor™ conjugate or tracer such as Kinase Tracer 178 to a kinase is detected by addition of a Eu-labeled anti-tag antibody. Binding of the tracer & antibody to a kinase results in a high degree of FRET, whereas displacement of the tracer with a kinase inhibitor results in a loss of FRET. Unlike many kinase activity assays, this assay is a simple mix and read assay, with no development steps.

Specifications

• Product Line: LanthaScreen™
• For Use With (Equipment): Microplate Reader
• Target: Kinases (Multiple)
• For Use With (Application): TR-FRET
• Assay: Kinase Binding Assay
• Content And Storage: Store at -20°C.
• Assay Entry: Biochemical binding/kinetic
• Label or Dye: Alexa Fluor 647
• Product Type: Kinase Tracer
• Quantity: 25 μL
• Format: 384-well plate
• Readout: Kinetic
• Shipping Condition: Dry Ice
• Target Entry: PTK6, DDR2, BMPR1A, RAF1 (cRAF) Y340D Y341D, ACVR1B, WNK2, TEC, DDR1, EPHB4, ERBB4, KIT V654A, TGFBR1, NLK, TGFBR2, EPHB3, BRAF V599E, BRAF, ACVR2B, ACVR2A

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov

For Research Use Only. Not for use in diagnostic procedures.