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Invitrogen™ Kindlin Recombinant Superclonal™ Antibody

Catalog No. 710862
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100 μg
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Catalog No. Quantity
71-086-2 100 μg
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Catalog No. 71-086-2 Supplier Invitrogen™ Supplier No. 710862
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Description

Rabbit Recombinant Superclonal Antibody

This antibody is predicted to react with Monkey, Cat, Dog and Horse. Recombinant rabbit Superclonal™ antibodies are unique offerings from Thermo Fisher Scientific. They are comprised of a selection of multiple different recombinant monoclonal antibodies, providing the best of both worlds - the sensitivity of polyclonal antibodies with the specificity of monoclonal antibodies - all delivered with the consistency only found in a recombinant antibody. While functionally the same as a polyclonal antibody - recognizing multiple epitope sites on the target and producing higher detection sensitivity for low abundance targets - a recombinant rabbit Superclonal™ antibody has a known mixture of light and heavy chains. The exact population can be produced in every lot, circumventing the biological variability typically associated with polyclonal antibody production. Note: Formerly called Recombinant polyclonal antibody, this product is now rebranded as Recombinant Superclonal™ antibody. The physical product and the performance remain unchanged.

Kindlin 1 is a member of the kindlin family of focal adhesion proteins and contains a FERM domain and pleckstrin homology domain. It is involved in integrin signaling, linkage of the cytoskeleton to the extracellular matrix, and cell adhesion. It is most often expressed in epithelial cells. When kindlin 1 is coexpressed with talin it helps to activate ITGA2B. It is required for keratinocyte proliferation, polarization of basal keratinocytes in the skin, and for normal cell shape. Mutations in kindlin 1 have been linked to Kindler syndrome, a recessive skin disorder involving blistering, photosensitivity, poikiloderma, and atrophy.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Kindlin
Applications Western Blot, Immunocytochemistry
Classification Recombinant Superclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.2
Gene FERMT1
Gene Accession No. Q9BQL6
Gene Alias 5830467P10Rik; C20orf42; DTGCU2; Fermitin family homolog 1; fermitin family homolog 1 (Drosophila); fermitin family member 1; FERMT1; FLJ20116; FLJ23423; KIND1; Kindlerin; kindlin 1; kindlin syndrome protein; Kindlin-1; RGD1306816; RP5-1056H1.1; UNC112 related protein 1; UNC-112 related protein 1; UNC112A; unc-112-related protein 1; URP1
Gene Symbols FERMT1
Host Species Rabbit
Immunogen Protein corresponding to Human FERMT1 (aa 200-409).
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 55612
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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