Invitrogen™ Kininogen Heavy Chain Monoclonal Antibody (2B5)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA110832

Catalog No. 01-671-860

Description

MA1-10832 detects High MW Kininogen, heavy chain, from human samples. MA1-10832 has been successfully used in ELISA and Western blot applications. The MA1-10832 immunogen is purified high molecular weight kininogen.

This gene uses alternative splicing to generate two different proteins- high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK). HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Also, bradykinin, a peptide causing numerous physiological effects, is released from HMWK. In contrast to HMWK, LMWK is not involved in blood coagulation. Three transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: Kininogen Heavy Chain
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with no preservative; pH 7.4
• Gene Accession No.: P01042
• Gene Symbols: KNG1
• Immunogen: Purified high molecular weight kininogen.
• Quantity: 200 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: ELISA, Western Blot
• Clone: 2B5
• Conjugate: Unconjugated
• Gene: KNG1
• Gene Alias: Alpha-2-thiol proteinase inhibitor; BDK; BK; Bradykinin; fitzgerald factor; High molecular weight kininogen; HMWK; Ile-Ser-Bradykinin; Kallidin I; Kallidin II; kininogen 1; kininogen-1; Kininogen-1 heavy chain; Kininogen-1 light chain; KNG; KNG1; Low molecular weight growth-promoting factor; Lysyl-bradykinin; T-kinin; Williams-Fitzgerald-Flaujeac factor
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 3827
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid