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Kir2.2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
SDP

Catalog No. p-7205898 Shop All Proteintech Group Inc Products
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50-172-9235 150 μL
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Catalog No. 50-172-9235 Supplier Proteintech Group Inc Supplier No. 141351AP150UL
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Rabbit Polyclonal Antibody

Inward rectifying potassium channel that is activated by phosphatidylinositol 4,5-bisphosphate and that probably participates in controlling the resting membrane potential in electrically excitable cells. Probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium.

Specifications

Antigen Kir2.2
Applications Flow Cytometry, Western Blot
Classification Polyclonal
Concentration 0.33 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene KCNJ12
Gene Accession No. P52187, P52188, Q14500
Gene Alias hIRK, hIRK1, hkir2.2x, IRK 2, IRK2, KCNJ12, kcnj12x, KCNJN1, Kir2.2, Kir2.2v
Gene Symbols KCNJ12
Host Species Rabbit
Immunogen Kir2.2 Fusion Protein Ag5349
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 117052, 16515, 3768
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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