Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
KIR2DS4 Rabbit anti-Human, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
$518.60
Specifications
| Antigen | KIR2DS4 |
|---|---|
| Concentration | 0.53 mg/mL |
| Applications | Immunocytochemistry, Immunofluorescence, Western Blot |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
50-173-3284
|
Proteintech Group Inc
211521AP150UL |
150 μL |
Each of 1 for $518.60
|
|
|||||
Description
Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules; thus, KIR proteins are thought to play an important role in regulation of the immune response.Specifications
| KIR2DS4 | |
| Immunocytochemistry, Immunofluorescence, Western Blot | |
| Unconjugated | |
| Rabbit | |
| Human | |
| P43632 | |
| 3809 | |
| KIR2DS4 Fusion Protein Ag15711 | |
| Primary | |
| -20°C | |
| KIR2DS4 |
| 0.53 mg/mL | |
| Polyclonal | |
| Liquid | |
| RUO | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| CD158I, KIR1D, KIR2DS4, KIR412, KKA3, MHC class I NK cell receptor, NKAT 8, NKAT8, p58 NK receptor CL 39/CL 17 | |
| KIR2DS4 | |
| IgG | |
| Antigen Affinity Chromatography | |
| Antibody |
Spot an opportunity for improvement?Share a Content Correction
Product Content Correction
The Fisher Scientific Encompass Program offers items which are not part of our distribution portfolio. These products typically do not have pictures or detailed descriptions. However, we are committed to improving your shopping experience. Please use the form below to provide feedback related to the content on this product.
Product Title