Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. KIR2DS4 Rabbit anti-Human, Polyclonal, Proteintech 

KIR2DS4 Rabbit anti-Human, Polyclonal, Proteintech
SDP

Catalog No. 501733284 Shop All Proteintech Group Inc Products
Encompass_Preferred
Change view
Click to view available options
Quantity:
150 μL
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
50-173-3284 150 μL
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Catalog No. 50-173-3284 Supplier Proteintech Group Inc Supplier No. 211521AP150UL
Only null left
Add to Cart
Add to Cart

Description

Rabbit Polyclonal Antibody

Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules; thus, KIR proteins are thought to play an important role in regulation of the immune response.

Specifications

Antigen KIR2DS4
Applications Immunocytochemistry, Immunofluorescence, Western Blot
Classification Polyclonal
Concentration 0.53 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene KIR2DS4
Gene Accession No. P43632
Gene Alias CD158I, KIR1D, KIR2DS4, KIR412, KKA3, MHC class I NK cell receptor, NKAT 8, NKAT8, p58 NK receptor CL 39/CL 17
Gene Symbols KIR2DS4
Host Species Rabbit
Immunogen KIR2DS4 Fusion Protein Ag15711
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3809
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
Show More Show Less
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.