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Invitrogen™ KLB Polyclonal Antibody
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Catalog No. PIPA544023
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100 μL
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PIPA544023 100 μL
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Catalog No. PIPA544023 Supplier Invitrogen™ Supplier No. PA544023
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Rabbit Polyclonal Antibody

Peptide sequence: DAYTIRRGLF YVDFNSKQKE RKPKSSAHYY KQIIRENGFS LKESTPDVQG Sequence homology: Cow: 100%; Dog: 93%; Guinea Pig: 85%; Horse: 93%; Human: 100%; Mouse: 100%; Pig: 93%; Rabbit: 86%; Rat: 100%.

KLB is a single-pass type III membrane protein. It contributes to the transcriptional repression of cholesterol 7-alpha-hydroxylase (CYP7A1), the rate-limiting enzyme in bile acid synthesis. KLB is probably inactive as a glycosidase. It increases the ability of FGFR1 and FGFR4 to bind FGF21.
TRUSTED_SUSTAINABILITY

Specifications

Antigen KLB
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene KLB
Gene Accession No. Q86Z14
Gene Alias AV071179; Betakl; betaKlotho; beta-klotho; BKL; Klb; Klb-ps1; klotho beta; klotho beta like; klotho beta, pseudogene 1; klotho beta-like protein; MGC142213; RGD1308227
Gene Symbols KLB
Host Species Rabbit
Immunogen Synthetic peptide directed towards the middle region of human KLB.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 152831
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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