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Invitrogen™ KLB Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA544023

Catalog No. PIPA544023


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Description

Description

Peptide sequence: DAYTIRRGLF YVDFNSKQKE RKPKSSAHYY KQIIRENGFS LKESTPDVQG Sequence homology: Cow: 100%; Dog: 93%; Guinea Pig: 85%; Horse: 93%; Human: 100%; Mouse: 100%; Pig: 93%; Rabbit: 86%; Rat: 100%.

KLB is a single-pass type III membrane protein. It contributes to the transcriptional repression of cholesterol 7-alpha-hydroxylase (CYP7A1), the rate-limiting enzyme in bile acid synthesis. KLB is probably inactive as a glycosidase. It increases the ability of FGFR1 and FGFR4 to bind FGF21.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

KLB
Polyclonal
Unconjugated
KLB
AV071179; Betakl; betaKlotho; beta-klotho; BKL; Klb; Klb-ps1; klotho beta; klotho beta like; klotho beta, pseudogene 1; klotho beta-like protein; MGC142213; RGD1308227
Rabbit
Affinity chromatography
RUO
152831
-20°C, Avoid Freeze/Thaw Cycles
Liquid
Immunohistochemistry, Western Blot
0.5 mg/mL
PBS with 2% sucrose and 0.09% sodium azide
Q86Z14
KLB
Synthetic peptide directed towards the middle region of human KLB.
100 μL
Primary
Human
Antibody
IgG
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