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Invitrogen™ KLRG1 Monoclonal Antibody (2F1), Brilliant Violet™ 711, eBioscience™, Invitrogen™
Description
KLRG1 (Killer cell lectin-like receptor G1, MAFA, 2F1-Ag) is a homodimeric member of the lectin-like type 2 transmembrane receptor family whose members contain characteristic immunoreceptor tyrosine-based inhibitory motifs (ITIMs) in their cytoplasmic domains. These ITIMs interact with the SH2 domains of protein phosphatases such as SHP-1. KLRG1 is an inhibitory receptor that is expressed on natural killer (NK) cells and certain T cells. NK cells are involved in the lysis of tumor cells and virus-infected cells, and mediate humoral and cell-mediated immune responses.
Specifications
Specifications
| Antigen | KLRG1 |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
| Clone | 2F1 |
| Concentration | 0.2 mg/mL |
| Conjugate | Brilliant Violet 711 |
| Formulation | PBS with BSA and 0.09% sodium azide; pH 7.2 |
| Gene | Klrg1 |
| Gene Accession No. | O88713 |
| Gene Alias | 2F1; 2F1-Ag; CLEC15A; C-type lectin domain family 15 member A; C-type lectin domain family 15, member A; ITIM-containing receptor MAFA-L; killer cell lectin like receptor G1; killer cell lectin-like receptor subfamily G member 1; killer cell lectin-like receptor subfamily G, member 1; Klrg1; Mafa; MAFA-2F1; MAFAL; MAFA-L; MAFA-LIKE; MAFA-like receptor; Mast cell function-associated antigen; mast cell function-associated antigen (ITIM-containing); mast cell function-associated antigen 2F1; natural killer cell receptor |
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