KRT19 Mouse anti-Human, Clone: UMAB2, liquid, UltraMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene UM570002

Catalog No. 50-168-5044

Description

Cytokeratin 19 is part of a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in human epithelial tissues by at least 20 different polypeptides. Cytokeratins range in molecular weight from 40-68 kDa and isoelectric pH between 4.9 - 7.8. The individual human cytokeratins are numbered 1 to 20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial maligcies. The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays. For example, cytokeratin 19 is not expressed in hepatocytes, therefore, it is useful in the identification of liver metastasis.

Specifications

• Antigen: KRT19
• Classification: Monoclonal
• Concentration: 0.5-1.0 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: P08727
• Gene Symbols: KRT19
• Immunogen: Recombit fragment expressed in E.coli corresponding to amino acids 240-390 of human CK19
• Quantity: 30 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Clone: UMAB2
• Conjugate: Unconjugated
• Gene: KRT19
• Gene Alias: CK19, K19, K1CS
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 3880
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid