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Invitrogen™ KRT84 Polyclonal Antibody
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Catalog No. PIPA599825
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PIPA599825 100 μL
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Catalog No. PIPA599825 Supplier Invitrogen™ Supplier No. PA599825
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total KRT84.

The Keratin multigene family is made of soft epithelial cytokeratins and hard hair Keratins. While the epithelial cytokeratins are involved in the layering and formation of epithelia, the hair Keratins are responsible for creating nails and hair. There are two types of Keratins: the acidic class I Keratin proteins and the basic/neutral class II Keratin proteins. Keratin 84, also known as KRT84, HB4 or KRTHB4, is a 600 amino acid protein that is expressed in hair follicles. Keratin 84 is a basic/neutral type II Keratin protein which heterodimerizes with type I Keratins to create hair and nails. The gene encoding Keratin 84 maps to human chromosome 12 which encodes over 1,100 genes and comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis and Kniest dysplasia.
TRUSTED_SUSTAINABILITY

Specifications

Antigen KRT84
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene KRT84
Gene Accession No. Q99M73, Q9NSB2
Gene Alias 65 kDa type II keratin; AV235125; hard keratin, type II, 4; HB4; HRb-1; K84; Kb24; keratin 84; keratin 84, type II; keratin complex 2, basic, gene 16; keratin complex 2, gene 16; keratin, hair, basic, 4; keratin, type II cuticular Hb4; Keratin-84; Krt2-16; Krt2-3; Krt84; KRTHB4; type II hair keratin 4; type II hair keratin Hb4; type II keratin Kb24; type-II keratin Kb24
Gene Symbols KRT84
Host Species Rabbit
Immunogen A synthesized peptide derived from human KRT84(Accession Q9NSB2), corresponding to amino acid residues G550-Y600.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 16680, 315320, 3890
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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