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Invitrogen™ KRTCAP2 Polyclonal Antibody
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Catalog No. PIPA571140
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100 μL
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PIPA571140 100 μL
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Catalog No. PIPA571140 Supplier Invitrogen™ Supplier No. PA571140
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Description

Rabbit Polyclonal Antibody

This target displays homology in the following species: Cow: 93%; Dog: 93%; Guinea Pig: 79%; Horse: 93%; Human: 100%; Mouse: 86%; Pig: 93%; Rabbit: 93%; Rat: 100%.

Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity (PubMed:22467853). May be involved in N-glycosylation of APP (amyloid-beta precursor protein). Can modulate gamma-secretase cleavage of APP by enhancing endoprotelysis of PSEN1 (PubMed:21768116). [UniProt].
TRUSTED_SUSTAINABILITY

Specifications

Antigen KRTCAP2
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene KRTCAP2
Gene Accession No. Q8N6L1
Gene Alias 0610010I12Rik; dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit KCP2; KCP2; KCP-2; keratinocyte associated protein 2; keratinocyte-associated protein 2; keratinocytes associated protein 2; KRTCAP2; LOW QUALITY PROTEIN: keratinocyte-associated protein 2; oligosaccharyl transferase subunit KCP2
Gene Symbols KRTCAP2
Host Species Rabbit
Immunogen synthetic peptide directed towards the C-terminal region of human KRTCAP2.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 200185
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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