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Apexbio Technology LLC U 73343 142878-12-4 25mg

Supplier: Apexbio Technology LLC B901325
U 73343 (CAS 142878-12-4) is a structural analog of U 73122 commonly utilized as an inactive control in studies investigating phospholipase C (PLC) activity Unlike U 73122 U 73343 does not inhibit PLC-mediated hydrolysis of phosphatidylinositol 4 5-bisphosphate a key step generating diacylglycerol and inositol 1 4 5-trisphosphate involved in intracellular signaling Through its lack of PLC antagonism U 73343 serves as a negative control to distinguish nonspecific or off-target effects in experiments analyzing processes such as hormone-induced calcium mobilization and gastric acid secretion thereby supporting accurate assessment of PLC-dependent signaling mechanisms
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