KU70/XRCC6 Mouse anti-Human, Mouse, Rat, Clone: 3C12D9, Proteintech

Mouse Monoclonal Antibody

Supplier:  Proteintech Group Inc 666071IG150UL

Catalog No. 50-173-7025

Description

XRCC6 is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus.

Specifications

• Antigen: KU70/XRCC6
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Accession No.: P12956, P23475
• Gene Symbols: Xrcc6
• Immunogen: KU70,XRCC6 Fusion Protein Ag21301
• Quantity: 150 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: 3C12D9
• Conjugate: Unconjugated
• Gene: XRCC6
• Gene Alias: 5 dRP lyase Ku70, 70 kDa subunit of Ku antigen, CTC75, CTCBF, DNA repair protein XRCC6, G22P1, KU70, ML8, Thyroid lupus autoantigen, TLAA, XRCC6
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 14375, 25019, 2547
• Content And Storage: -20°C
• Form: Liquid