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Invitrogen™ KV1.1 (KCNA1) Polyclonal Antibody
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Catalog No. PIPA540991
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100 μL
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PIPA540991 100 μL
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Catalog No. PIPA540991 Supplier Invitrogen™ Supplier No. PA540991
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Description

Rabbit Polyclonal Antibody

Peptide sequence: ISIVIFCLET LPELKDDKDF TGTVHRIDNT TVIYNSNIFT DPFFIVETLC Sequence homology: Dog: 100%; Guinea Pig: 79%; Horse: 86%; Human: 100%; Mouse: 93%; Pig: 100%; Rat: 93%.

This gene encodes a voltage-gated delayed potassium channel that is phylogenetically related to the Drosophila Shaker channel. The encoded protein has six putative transmembrane segments, and the loop between S5 and S6 forms the pore and contains the conserved selectivity filter motif. The functional channel is a homotetramer. The N-terminus of the channel is associated with beta subunits that can modify the inactivation properties of the channel as well as affect expression levels. The C-terminus of the channel is complexed to a PDZ domain protein that is responsible for channel targeting. Mutations in this gene have been associated with myokymia with periodic ataxia.
TRUSTED_SUSTAINABILITY

Specifications

Antigen KV1.1 (KCNA1)
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene Kcna1
Gene Accession No. Q09470
Gene Alias AEMK; AI840627; brain potassium channel protein-1; EA1; HBK1; HUK1; IA; Kca1-1; Kcna; Kcna1; Kcpvd; Kv1.1; MBK1; mceph; megencephaly; MGC126782; MGC138385; MK1; Mk-1; MKI; potassium (K+) channel protein voltage dependent; potassium channel, voltage gated shaker related subfamily A, member 1; potassium voltage gated channel shaker related subfamily member 1; potassium voltage gated channel, shaker related subfamily, member 1; potassium voltage-gated channel subfamily A member 1; potassium voltage-gated channel, shaker-related subfamily, member 1; potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia); RBK1; RBKI; RCK1; Shak; Voltage-gated K(+) channel HuKI; voltage-gated potassium channel HBK1; Voltage-gated potassium channel subunit Kv1.1
Gene Symbols Kcna1
Host Species Rabbit
Immunogen Synthetic peptide directed towards the middle region of human KCNA1.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3736
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

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