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Invitrogen™ KV3.2 (KCNC2) Polyclonal Antibody
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Catalog No. PIPA599182
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PIPA599182 100 μL
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Catalog No. PIPA599182 Supplier Invitrogen™ Supplier No. PA599182
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total KCNC2.

Voltage-gated K+ channels in the plasma membrane control the repolarization and the frequency of action potentials in neurons, muscles and other excitable cells. The KV gene family encodes more than 30 proteins that comprise the subunits of the K+ channels. The subunits vary in their gating and permeation properties, subcellular distribution and expression patterns. Functional KV channels assemble as tetramers consisting of pore-forming alpha subunits, which include the KV1, KV2, KV3, KV4 and KV9 proteins, as well as accessory subunits that modify the gating properties of the coexpressed KV subunits. KV3.2 is a multipass membrane protein that regulates the voltage-dependent K+ permeability of excitable membranes. The tail of KV3.2 may be influential in the targeting of the channel to specific subcellular compartments and/or the regulation of channel activity.
TRUSTED_SUSTAINABILITY

Specifications

Antigen KV3.2 (KCNC2)
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene KCNC2
Gene Accession No. P22462, Q14B80, Q96PR1
Gene Alias AW047325; B230117I07; KCNC2; KShIIIA; Kv3.2; Potassium channel voltage-gated Shaw-related subfamily C member 2; potassium channel, voltage gated Shaw related subfamily C, member 2; potassium channel, voltage gated Shaw-related subfamily C, member 2; potassium voltage gated channel, Shaw-related subfamily, member 2; potassium voltage-gated channel subfamily C member 2; potassium voltage-gated channel, Shaw-related subfamily, member 2; shaw-like potassium channel; Voltage-gated potassium channel Kv3.2; voltage-gated potassium channel subunit Kv3.2
Gene Symbols KCNC2
Host Species Rabbit
Immunogen A synthesized peptide derived from human KCNC2(Accession Q96PR1), corresponding to amino acid residues G606-L638.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 246153, 268345, 3747
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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